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Great investors · Stanley Druckenmiller · Q4 2025

What Stanley Druckenmiller bought and sold in Q4 2025

Duquesne Family Office 13F portfolio as of Dec 31, 2025: 58 positions worth $4.2 bn. Largest: NTRA, XLF, INSM, RSP. Filed with the SEC on Feb 17, 2026.

The 13F is filed by Duquesne Family Office, not by Stanley Druckenmiller personally: these are the whole firm's positions. A “position” is a distinct security in the filing (by CUSIP); share classes of the same company are shown added together.

Buys in Q4 2025

Sells in Q4 2025

46 companies with material moves, out of 81 positions with a change. Only moves of 0.5 points of the portfolio or more are listed, measured as “traded weight” (what was bought or sold, excluding price effects). Smaller changes exist and are not listed: a position may have gone up or down without appearing above.

The full 13F, line by line

Duquesne Family Office's Q4 2025 13F lists 58 lines of US-listed securities worth $4.2 bn; the largest is NTRA at 13.6% of the portfolio. It was accepted by the SEC on Feb 17, 2026 at 2:44 PM ET.

Against the previous quarter, it opened 26 positions (XLF, RSP, EWZ and AA and 22 more), closed 29 (META, CRS, C and TWLO and 25 more), added to 13 (GOOGL, SE, AMZN and TBBB and 9 more) and trimmed 14 (NTRA, TEVA, INSM and TSM and 10 more). 5 lines show the same number of shares.

#CompanySharesValueWeightChange in shares
1Natera NTRA2.5 M$575M13.6%−22%
2State Street Financial Select Sector ETF XLF5.5 M$301M7.13%new
3Insmed INSM1.5 M$258M6.11%−39%
4Invesco Exchange Traded Fund T RSP1.2 M$225M5.33%new
5TEVA Pharmaceutical Industries TEVA5.9 M$183M4.34%−65%
6Woodward WWD590,930$179M4.23%−6.6%
7Amazon.com AMZN737,940$170M4.04%+69%
8Taiwan Semiconductor Manufacturing TSM543,085$165M3.91%−29%
9Coupang CPNG6.8 M$160M3.79%+46%
10Alphabet GOOGL385,000$121M2.86%+277%
11Sea SE944,120$120M2.85%+244%
12Ishares EWZ3.6 M$113M2.67%new
13NewAmsterdam Pharma NAMS3.1 M$108M2.55%+60%
14MercadoLibre MELI47,149$95.0M2.25%−19%
15BBB Foods TBBB2.7 M$89.3M2.12%+126%
16Restaurant Brands International QSR1.2 M$82.5M1.95%+6.9%
17Cogent Biosciences COGT2.2 M$78.7M1.86%+109%
18Alcoa AA1.4 M$73.1M1.73%new
19Entegris ENTG844,160$71.1M1.69%new
20Docusign DOCU1.0 M$69.7M1.65%−40%
21Lattice Semiconductor LSCC925,970$68.1M1.61%new
22Bloom Energy BE740,545$64.3M1.52%new
23Wabtec WAB300,110$64.1M1.52%no change
24Roku ROKU582,980$63.2M1.50%−29%
25Figure Technology Solutions FIGR1.5 M$62.9M1.49%−27%
26CRH public CRH474,955$59.3M1.40%+21%
27Option Care Health OPCH1.7 M$55.6M1.32%+79%
28iShares Msci Emerging Market ETF EEM902,500$49.4M1.17%−53%
29Delta Air Lines DAL650,910$45.2M1.07%new
30United Airlines Holdings UAL348,400$39.0M0.92%new
31Stubhub Holdings STUB2.3 M$31.2M0.74%−46%
32ON Semiconductor ON536,260$29.0M0.69%new
33Flutter Entertainment FLUT115,245$24.8M0.59%no change
34PureCycle Technologies PCT2.9 M$24.7M0.59%+25%
35AEVA Technologies AEVA1.8 M$24.2M0.57%no change
36Goldman Sachs Group GS27,500$24.2M0.57%new
37Cleveland-cliffs CLF1.7 M$23.2M0.55%−36%
38YPF Sociedad Anonima YPF606,990$21.9M0.52%+429%
39STMicroelectronics STM773,555$20.1M0.48%new
40Unity Software U410,020$18.1M0.43%−54%
41Southern Copper Corp/ SCCO120,817$17.3M0.41%new
42Daktronics DAKT852,960$16.9M0.40%−41%
43RH RH88,200$15.8M0.37%new
44Chipotle Mexican Grill CMG391,930$14.5M0.34%+68%
45Protagonist Therapeutics PTGX159,700$13.9M0.33%no change
46Zillow Group Z192,640$13.1M0.31%new
47Cidara Therapeutics CDTX49,495$10.9M0.26%new
48Philip Morris International PM67,400$10.8M0.26%new
49American Airlines Group AAL639,785$9.8M0.23%new
50Argan AGX30,000$9.4M0.22%new
51DoorDash DASH35,900$8.1M0.19%new
52Progyny PGNY295,115$7.6M0.18%new
53EchoStar ECHO60,765$6.6M0.16%no change
54ADMA Biologics ADMA252,200$4.6M0.11%new
55Almonty Industries ALM469,880$4.1M0.10%new
56Wolfspeed WOLF186,900$3.3M0.08%new
57Wave Life Sciences 173,000$2.9M0.07%new
58Neptune Insurance Holdings NP20,000$583K0.01%new

Positions it closed (29)

One row per line of the filing (by CUSIP): share classes of the same company are listed separately here. “Change in shares” compares the count with the previous quarter, split-adjusted; the value is the one reported in the 13F at quarter end, not today's price.

Original documents: Duquesne Family Office's 13F filings on EDGAR (SEC) ↗

Full 13F of Duquesne Family Office: sectors and history →

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Source: 13F filings with the SEC. A 13F shows the portfolio at quarter-end and is filed up to 45 days later: these are not real-time positions. Not investment advice.

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